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After controlling for confounders, such as obesity and smoking, the investigators generated a PRS to model genetic risk and found an additive interaction between genetic susceptibility and air pollution, such that individuals with high genetic risk and high levels of exposure to air pollution were at greatest risk of developing lung cancer (PM 2.5 : HR 1.71, 95% CI 1.452.02) relative to those with low genetic risk and low air pollution exposure

It is more frequent among older adults, vegetarians, vegans, individuals with gastrointestinal disorders, and during pregnancy when requirements increase

D., Inda, A

Finally, establish realistic timelines for metabolic improvements, recognizing that benefits typically emerge gradually over several months of treatment

They aren't mutually exclusive -- many patients benefit from both